We will also discuss the potential of emergent organoid systems to emulate and interrogate the dynamics of lineage specification at cellular resolution.Ĭopyright © 2019 Elsevier Ltd. Ectocardia (ecto - cardia): This congenital condition is characterized by. Ectoblast (ecto - blast): a synonym for an epiblast or an ectoderm. An antigen is any substance that elicits an antibody immune response. This review discusses the events associated with mesoderm specification, highlighting the reconstruction of putative developmental trajectories facilitated by recent single-cell 'omic' data. Ectoantigen (ecto - antigen): An antigen that is located on the surface or exterior of a microbe is known as an ectoantigen. A long-standing question pertains how this panoply of mesodermal cell types arises in a stereotypical fashion in time and space. Cells of mesodermal origin are the most abundant in the human body, representing a great variety of cell types, including the musculoskeletal system (bone, cartilage and muscle), cardiovascular system (heart, blood and blood vessels), as well as the connective tissues found throughout our bodies. The three germ layers - mesoderm, endoderm and ectoderm - constituting the cellular blueprint for the tissues and organs that will form during embryonic development, are specified at gastrulation.
